Constitutive TL1A (TNFSF15) Expression on Lymphoid or Myeloid Cells Leads to Mild Intestinal Inflammation and Fibrosis

TL1A is a member of the TNF superfamily and its expression is increased in the mucosa of inflammatory bowel disease patients. Moreover, a subset of Crohn's disease (CD) patients with the risk TL1A haplotype is associated with elevated TL1A expression and a more severe disease course. To investi...

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Autors principals: Shih, David Q., Barrett, Robert, Zhang, Xiaolan, Yeager, Nicole, Koon, Hon Wai, Phaosawasdi, Piangwarin, Song, Yahui, Ko, Brian, Wong, Michelle H., Michelsen, Kathrin S., Martins, Gislaine, Pothoulakis, Charalabos, Targan, Stephan R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019214/
https://ncbi.nlm.nih.gov/pubmed/21264313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016090
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