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Substance P mediates antiapoptotic responses in human colonocytes by Akt activation
We examined the hypothesis that substance P (SP) and the neurokinin-1 receptor (NK-1R), both in vitro and in vivo, promote mucosal healing during recovery from colitis by stimulating antiapoptotic pathways in human colonic epithelial cells. For the in vitro experiments, human nontransformed NCM460 c...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794289/ https://ncbi.nlm.nih.gov/pubmed/17264209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610664104 |
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