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Neurotensin stimulates expression of early growth response gene-1 and EGF receptor through MAP kinase activation in human colonic epithelial cells

Neurotensin (NT) is a highly expressed gastrointestinal (GI) neuropeptide, which modulates GI motility, secretion and cell growth as well as intestinal inflammation. Since EGF receptor is highly expressed in human colon cancer cells, we sought to examine whether NT stimulation contributes to the EGF...

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Main Authors: Zhao, Dezheng, Zhan, Yanai, Zeng, Huiyan, Koon, Hon Wai, Moyer, Mary P., Pothoulakis, Charalabos
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685406/
https://ncbi.nlm.nih.gov/pubmed/17230532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.22407
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