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Neurotensin stimulates expression of early growth response gene-1 and EGF receptor through MAP kinase activation in human colonic epithelial cells

Neurotensin (NT) is a highly expressed gastrointestinal (GI) neuropeptide, which modulates GI motility, secretion and cell growth as well as intestinal inflammation. Since EGF receptor is highly expressed in human colon cancer cells, we sought to examine whether NT stimulation contributes to the EGF...

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Autors principals: Zhao, Dezheng, Zhan, Yanai, Zeng, Huiyan, Koon, Hon Wai, Moyer, Mary P., Pothoulakis, Charalabos
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685406/
https://ncbi.nlm.nih.gov/pubmed/17230532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.22407
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