Impact of Sarcoplasmic Reticulum Calcium Release on Calcium Dynamics and Action Potential Morphology in Human Atrial Myocytes: A Computational Study

Por Koivumäki, Jussi T., Korhonen, Topi, Tavi, Pasi
Publicado em 2011

Calcium signalling in developing cardiomyocytes: implications for model systems and disease

Por Louch, William E, Koivumäki, Jussi T, Tavi, Pasi
Publicado no J Physiol (2015)

In Silico Screening of the Key Cellular Remodeling Targets in Chronic Atrial Fibrillation

Por Koivumäki, Jussi T., Seemann, Gunnar, Maleckar, Mary M., Tavi, Pasi
Publicado em 2014

Regulation of excitation-contraction coupling in mouse cardiac myocytes: integrative analysis with mathematical modelling

Por Koivumäki, Jussi T, Korhonen, Topi, Takalo, Jouni, Weckström, Matti, Tavi, Pasi
Publicado em 2009

Local Ca(2+) releases enable rapid heart rates in developing cardiomyocytes

Por Korhonen, Topi, Rapila, Risto, Ronkainen, Veli-Pekka, Koivumäki, Jussi T, Tavi, Pasi
Publicado em 2010

Benchmarking electrophysiological models of human atrial myocytes

Por Wilhelms, Mathias, Hettmann, Hanne, Maleckar, Mary M., Koivumäki, Jussi T., Dössel, Olaf, Seemann, Gunnar
Publicado em 2013

Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions

Por Paci, Michelangelo, Koivumäki, Jussi T., Lu, Hua Rong, Gallacher, David J., Passini, Elisa, Rodriguez, Blanca
Publicado no Front Pharmacol (2021)

Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

Por Vagos, Márcia, van Herck, Ilsbeth G. M., Sundnes, Joakim, Arevalo, Hermenegild J., Edwards, Andrew G., Koivumäki, Jussi T.
Publicado no Front Physiol (2018)

hiPSC-Derived Cardiomyocyte Model of LQT2 Syndrome Derived from Asymptomatic and Symptomatic Mutation Carriers Reproduces Clinical Differences in Aggregates but Not in Single Cells

Por Shah, Disheet, Prajapati, Chandra, Penttinen, Kirsi, Cherian, Reeja Maria, Koivumäki, Jussi T., Alexanova, Anna, Hyttinen, Jari, Aalto-Setälä, Katriina
Publicado no Cells (2020)

Ca(2+)–calmodulin-dependent protein kinase II represses cardiac transcription of the L-type calcium channel α(1C)-subunit gene (Cacna1c) by DREAM translocation

Por Ronkainen, Jarkko J, Hänninen, Sandra L, Korhonen, Topi, Koivumäki, Jussi T, Skoumal, Reka, Rautio, Sini, Ronkainen, Veli-Pekka, Tavi, Pasi
Publicado em 2011

Na(+) current expression in human atrial myofibroblasts: identity and functional roles

Por Koivumäki, Jussi T., Clark, Robert B., Belke, Darrell, Kondo, Colleen, Fedak, Paul W. M., Maleckar, Mary M. C., Giles, Wayne R.
Publicado em 2014

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart

Por Naumenko, Nikolay, Huusko, Jenni, Tuomainen, Tomi, Koivumäki, Jussi T., Merentie, Mari, Gurzeler, Erika, Alitalo, Kari, Kivelä, Riikka, Ylä-Herttuala, Seppo, Tavi, Pasi
Publicado no Front Physiol (2017)

Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling

Por Koivumäki, Jussi T., Naumenko, Nikolay, Tuomainen, Tomi, Takalo, Jouni, Oksanen, Minna, Puttonen, Katja A., Lehtonen, Šárka, Kuusisto, Johanna, Laakso, Markku, Koistinaho, Jari, Tavi, Pasi
Publicado no Front Physiol (2018)

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I(bk,Ca))

Por Horváth, András, Christ, Torsten, Koivumäki, Jussi T., Prondzynski, Maksymilian, Zech, Antonia T. L., Spohn, Michael, Saleem, Umber, Mannhardt, Ingra, Ulmer, Bärbel, Girdauskas, Evaldas, Meyer, Christian, Hansen, Arne, Eschenhagen, Thomas, Lemoine, Marc D.
Publicado no Cells (2020)

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Por Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie
Publicado no EMBO Mol Med (2019)