Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I(bk,Ca))

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) represent an unlimited source of human CMs that could be a standard tool in drug research. However, there is concern whether hiPSC-CMs express all cardiac ion channels at physiological level and whether they might express non-car...

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Vydáno v:Cells
Hlavní autoři: Horváth, András, Christ, Torsten, Koivumäki, Jussi T., Prondzynski, Maksymilian, Zech, Antonia T. L., Spohn, Michael, Saleem, Umber, Mannhardt, Ingra, Ulmer, Bärbel, Girdauskas, Evaldas, Meyer, Christian, Hansen, Arne, Eschenhagen, Thomas, Lemoine, Marc D.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7017352/
https://ncbi.nlm.nih.gov/pubmed/31968557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9010253
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