Contractile Work Contributes to Maturation of Energy Metabolism in hiPSC-Derived Cardiomyocytes

Energy metabolism is a key aspect of cardiomyocyte biology. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a promising tool for biomedical application, but they are immature and have not undergone metabolic maturation related to early postnatal development. To assess whet...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Ulmer, Bärbel M., Stoehr, Andrea, Schulze, Mirja L., Patel, Sajni, Gucek, Marjan, Mannhardt, Ingra, Funcke, Sandra, Murphy, Elizabeth, Eschenhagen, Thomas, Hansen, Arne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919410/
https://ncbi.nlm.nih.gov/pubmed/29503093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.039
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