Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) may serve as a new assay for drug testing in a human context, but their validity particularly for the evaluation of inotropic drug effects remains unclear. In this blinded analysis, we compared the effects of 10 indicator compound...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Mannhardt, Ingra, Eder, Alexandra, Dumotier, Berengere, Prondzynski, Maksymilian, Krämer, Elisabeth, Traebert, Martin, Söhren, Klaus-Dieter, Flenner, Frederik, Stathopoulou, Konstantina, Lemoine, Marc D., Carrier, Lucie, Christ, Torsten, Eschenhagen, Thomas, Hansen, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Cardiomyocyte Contractility in Engineered Heart Tissue
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837217/
https://ncbi.nlm.nih.gov/pubmed/28453742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx081
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados