Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

Human induced pluripotent stem cell (hiPSC) cardiomyocytes (CMs) show less negative resting membrane potential (RMP), which is attributed to small inward rectifier currents (I(K1)). Here, I(K1) was measured in hiPSC-CMs (proprietary and commercial cell line) cultured as monolayer (ML) or 3D engineer...

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Publicado no:Stem Cell Reports
Main Authors: Horváth, András, Lemoine, Marc D., Löser, Alexandra, Mannhardt, Ingra, Flenner, Frederik, Uzun, Ahmet Umur, Neuber, Christiane, Breckwoldt, Kaja, Hansen, Arne, Girdauskas, Evaldas, Reichenspurner, Hermann, Willems, Stephan, Jost, Norbert, Wettwer, Erich, Eschenhagen, Thomas, Christ, Torsten
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918194/
https://ncbi.nlm.nih.gov/pubmed/29429959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.012
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