Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions

Objectives: Improvements in human stem cell-derived cardiomyocyte (hSC-CM) technology have promoted their use for drug testing and disease investigations. Several in silico hSC-CM models have been proposed to augment interpretation of experimental findings through simulations. This work aims to asse...

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Vydáno v:Front Pharmacol
Hlavní autoři: Paci, Michelangelo, Koivumäki, Jussi T., Lu, Hua Rong, Gallacher, David J., Passini, Elisa, Rodriguez, Blanca
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8033762/
https://ncbi.nlm.nih.gov/pubmed/33841140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.604713
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