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Impact of Sarcoplasmic Reticulum Calcium Release on Calcium Dynamics and Action Potential Morphology in Human Atrial Myocytes: A Computational Study

Electrophysiological studies of the human heart face the fundamental challenge that experimental data can be acquired only from patients with underlying heart disease. Regarding human atria, there exist sizable gaps in the understanding of the functional role of cellular Ca(2+) dynamics, which diffe...

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Detalhes bibliográficos
Main Authors: Koivumäki, Jussi T., Korhonen, Topi, Tavi, Pasi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029229/
https://ncbi.nlm.nih.gov/pubmed/21298076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001067
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