Ca(2+)–calmodulin-dependent protein kinase II represses cardiac transcription of the L-type calcium channel α(1C)-subunit gene (Cacna1c) by DREAM translocation

ABSTRACT: Recent studies have demonstrated that changes in the activity of calcium–calmodulin-dependent protein kinase II (CaMKII) induce a unique cardiomyocyte phenotype through the regulation of specific genes involved in excitation–contraction (E–C)-coupling. To explain the transcriptional effect...

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Main Authors: Ronkainen, Jarkko J, Hänninen, Sandra L, Korhonen, Topi, Koivumäki, Jussi T, Skoumal, Reka, Rautio, Sini, Ronkainen, Veli-Pekka, Tavi, Pasi
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2011
Teme:
Molecular and Cellular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112547/
https://ncbi.nlm.nih.gov/pubmed/21486818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.201400
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