Twisting mice move the dystonia field forward

Por Petersén, Åsa, Kirik, Deniz
Publicado em 2014

Presynaptic dopaminergic compartment determines the susceptibility to L-DOPA–induced dyskinesia in rats

Por Ulusoy, Ayse, Sahin, Gurdal, Kirik, Deniz
Publicado em 2010

Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson's Disease

Por Cederfjäll, Erik, Broom, Lauren, Kirik, Deniz
Publicado no Mol Ther (2015)

Overexpression of Glial Cell Line-Derived Neurotrophic Factor Using a Lentiviral Vector Induces Time- and Dose-Dependent Downregulation of Tyrosine Hydroxylase in the Intact Nigros...

Por Georgievska, Biljana, Kirik, Deniz, Björklund, Anders
Publicado no J Neurosci (2004)

Growth and Functional Efficacy of Intrastriatal Nigral Transplants Depend on the Extent of Nigrostriatal Degeneration

Por Kirik, Deniz, Winkler, Christian, Björklund, Anders
Publicado no J Neurosci (2001)

Design of a Single AAV Vector for Coexpression of TH and GCH1 to Establish Continuous DOPA Synthesis in a Rat Model of Parkinson's Disease

Por Cederfjäll, Erik, Sahin, Gurdal, Kirik, Deniz, Björklund, Tomas
Publicado em 2012

Animal Models of Parkinson’s Disease: limits and relevance to neuroprotection studies

Por Bezard, Erwan, Yue, Zhenyu, Kirik, Deniz, Spillantini, Maria Grazia
Publicado em 2012

Long-Term rAAV-Mediated Gene Transfer of GDNF in the Rat Parkinson's Model: Intrastriatal But Not Intranigral Transduction Promotes Functional Regeneration in the Lesioned Nigrostr...

Por Kirik, Deniz, Rosenblad, Carl, Björklund, Anders, Mandel, Ronald J.
Publicado no J Neurosci (2000)

Microglia Acquire Distinct Activation Profiles Depending on the Degree of α-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease

Por Sanchez-Guajardo, Vanesa, Febbraro, Fabia, Kirik, Deniz, Romero-Ramos, Marina
Publicado em 2010

Dose Optimization for Long-term rAAV-mediated RNA Interference in the Nigrostriatal Projection Neurons

Por Ulusoy, Ayse, Sahin, Gurdal, Björklund, Tomas, Aebischer, Patrick, Kirik, Deniz
Publicado em 2009

The Functional Impact of the Intrastriatal Dopamine Neuron Grafts in Parkinsonian Rats Is Reduced with Advancing Disease

Por Breysse, Nathalie, Carlsson, Thomas, Winkler, Christian, Björklund, Anders, Kirik, Deniz
Publicado no J Neurosci (2007)

Serotonin Neuron Transplants Exacerbate l-DOPA- Induced Dyskinesias in a Rat Model of Parkinson's Disease

Por Carlsson, Thomas, Carta, Manolo, Winkler, Christian, Björklund, Anders, Kirik, Deniz
Publicado no J Neurosci (2007)

Identification of Dopaminergic Neurons of Nigral and Ventral Tegmental Area Subtypes in Grafts of Fetal Ventral Mesencephalon Based on Cell Morphology, Protein Expression, and Effe...

Por Thompson, Lachlan, Barraud, Perrine, Andersson, Elin, Kirik, Deniz, Björklund, Anders
Publicado no J Neurosci (2005)

Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson’s disease

Por Björklund, Tomas, Carlsson, Thomas, Cederfjäll, Erik Ahlm, Carta, Manolo, Kirik, Deniz
Publicado em 2010

A general chemical method to regulate protein stability in the mammalian central nervous system

Por Iwamoto, Mari, Björklund, Tomas, Lundberg, Cecilia, Kirik, Deniz, Wandless, Thomas J.
Publicado em 2010

Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue

Por Soylu-Kucharz, Rana, Adlesic, Natalie, Baldo, Barbara, Kirik, Deniz, Petersén, Åsa
Publicado no Sci Rep (2015)

Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity

Por Ledri, Marco, Madsen, Marita Grønning, Nikitidou, Litsa, Kirik, Deniz, Kokaia, Merab
Publicado no J Neurosci (2014)

Preserved Function of Afferent Parvalbumin-Positive Perisomatic Inhibitory Synapses of Dentate Granule Cells in Rapidly Kindled Mice

Por Hansen, Marita G., Ledri, Litsa N., Kirik, Deniz, Kokaia, Merab, Ledri, Marco
Publicado no Front Cell Neurosci (2018)

Enhanced Dopamine in Prodromal Schizophrenia (EDiPS): a new animal model of relevance to schizophrenia

Por Petty, Alice, Cui, Xiaoying, Tesiram, Yasvir, Kirik, Deniz, Howes, Oliver, Eyles, Darryl
Publicado no NPJ Schizophr (2019)

Functional Convergence of Dopaminergic and Cholinergic Input Is Critical for Hippocampus-Dependent Working Memory

Por Wisman, Liselijn A. B., Sahin, Gurdal, Maingay, Matthew, Leanza, Giampiero, Kirik, Deniz
Publicado no J Neurosci (2008)