Prediction of Acquired Taxane Resistance Using a Personalized Pathway-Based Machine Learning Method

per Kim, Young Rae, Kim, Dongha, Kim, Sung Young
Publicat a Cancer Res Treat (2019)

Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1

per Vikram, Ajit, Kim, Young-Rae, Kumar, Santosh, Li, Qiuxia, Kassan, Modar, Jacobs, Julia S., Irani, Kaikobad
Publicat a Nat Commun (2016)

Personalized Prediction of Acquired Resistance to EGFR-Targeted Inhibitors Using a Pathway-Based Machine Learning Approach

per Kim, Young Rae, Kim, Yong Wan, Lee, Suh Eun, Yang, Hye Won, Kim, Sung Young
Publicat a Cancers (Basel) (2019)

Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction

per Kim, Young-Rae, Kim, Cuk-Seong, Naqvi, Asma, Kumar, Ajay, Kumar, Santosh, Hoffman, Timothy A., Irani, Kaikobad
Publicat 2012

Redox Factor-1 Activates Endothelial SIRTUIN1 through Reduction of Conserved Cysteine Sulfhydryls in Its Deacetylase Domain

per Jung, Saet-Byel, Kim, Cuk-Seong, Kim, Young-Rae, Naqvi, Asma, Yamamori, Tohru, Kumar, Santosh, Kumar, Ajay, Irani, Kaikobad
Publicat 2013

MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1

per Kassan, Modar, Vikram, Ajit, Li, Qiuxia, Kim, Young-Rae, Kumar, Santosh, Gabani, Mohanad, Liu, Jing, Jacobs, Julia S., Irani, Kaikobad
Publicat a Sci Rep (2017)

P66Shc-induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1

per Li, Qiuxia, Kim, Young-Rae, Vikram, Ajit, Kumar, Santosh, Kassan, Modar, Gabani, Mohanad, Lee, Sang Ki, Jacobs, Julia S, Irani, Kaikobad
Publicat a Arterioscler Thromb Vasc Biol (2016)

Mulberry Fruit Extract Protects Pancreatic β-Cells against Hydrogen Peroxide-Induced Apoptosis via Antioxidative Activity

per Lee, Jong Seok, Kim, Young Rae, Park, Jun Myoung, Ha, Suk-Jin, Kim, Young Eon, Baek, Nam In, Hong, Eock Kee
Publicat a Molecules (2014)

Canonical Wnt signaling induces vascular endothelial dysfunction via p66(Shc)-regulated reactive oxygen species

per Vikram, Ajit, Kim, Young-Rae, Kumar, Santosh, Naqvi, Asma, Hoffman, Timothy A., Kumar, Ajay, Miller, Francis J., Kim, Cuk-Seong, Irani, Kaikobad
Publicat a Arterioscler Thromb Vasc Biol (2014)

Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice.

per Gaddam, Ravinder Reddy, Kim, Young-Rae, Li, Quixia, Jacobs, Julia S, Gabani, Mohanad, Mishra, Akansha, Promes, Joseph A, Imai, Yumi, Irani, Kaikobad, Vikram, Ajit
Publicat a Biochem Biophys Res Commun (2020)

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction

per Kumar, Santosh, Kim, Young-Rae, Vikram, Ajit, Naqvi, Asma, Li, Qiuxia, Kassan, Modar, Kumar, Vikas, Bachschmid, Markus M., Jacobs, Julia S., Kumar, Ajay, Irani, Kaikobad
Publicat a Proc Natl Acad Sci U S A (2017)

Corrigendum: Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress

per Kassan, Modar, Vikram, Ajit, Kim, Young-Rae, Li, Qiuxia, Kassan, Adam, Patel, Hemal H., Kumar, Santosh, Gabani, Mohanad, Liu, Jing, Jacobs, Julia S., Irani, Kaikobad
Publicat a Sci Rep (2017)

MiR-204 regulates type 1 IP(3)R to control vascular smooth muscle cell contractility and blood pressure

per Gabani, Mohanad, Liu, Jing, Ait-Aissa, Karima, Koval, Olha, Kim, Young-Rae, Castañeda, Diana, Vikram, Ajit, Jacobs, Julia S., Grumbach, Isabella, Trebak, Mohamed, Irani, Kaikobad, Kassan, Modar
Publicat a Cell Calcium (2019)

Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc

per Kim, Cuk-Seong, Kim, Young-Rae, Naqvi, Asma, Kumar, Santosh, Hoffman, Timothy A., Jung, Saet-Byel, Kumar, Ajay, Jeon, Byeong-Hwa, McNamara, Dennis M., Irani, Kaikobad
Publicat 2011

Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death

per Seok, Jeong Ho, Park, Kyeong Ah, Byun, Hee Sun, Won, Minho, Shin, Sanghee, Choi, Byung-Lyul, Lee, Hyunji, Kim, Young-Rae, Hong, Jang Hee, Park, Jongsun, Hur, Gang Min
Publicat 2008

Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice

per Gaddam, Ravinder Reddy, Jacobsen, Veronica Peotta, Kim, Young-Rae, Gabani, Mohanad, Jacobs, Julia S., Dhuri, Karishma, Kumar, Santosh, Kassan, Modar, Li, Qiuxia, Bahal, Raman, Roghair, Robert, Irani, Kaikobad, Vikram, Ajit
Publicat a Sci Rep (2020)

A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expression

per Naqvi, Asma, Hoffman, Timothy A., DeRicco, Jeremy, Kumar, Ajay, Kim, Cuk-Seong, Jung, Saet-Byel, Yamamori, Tohru, Kim, Young-Rae, Mehdi, Fardeen, Kumar, Santosh, Rankinen, Tuomo, Ravussin, Eric, Irani, Kaikobad
Publicat 2010

Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase

per Byun, Hee Sun, Won, Minho, Park, Kyeong Ah, Kim, Young-Rae, Choi, Byung Lyul, Lee, Hyunji, Hong, Jang Hee, Piao, Longzhen, Park, Jongsun, Kim, Jin Man, Kweon, Gi Ryang, Kang, Sung Hyun, Han, Jin, Hur, Gang Min
Publicat 2008

Two-terminal floating-gate memory with van der Waals heterostructures for ultrahigh on/off ratio

per Vu, Quoc An, Shin, Yong Seon, Kim, Young Rae, Nguyen, Van Luan, Kang, Won Tae, Kim, Hyun, Luong, Dinh Hoa, Lee, Il Min, Lee, Kiyoung, Ko, Dong-Su, Heo, Jinseong, Park, Seongjun, Lee, Young Hee, Yu, Woo Jong
Publicat a Nat Commun (2016)

Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC

per Kim, Young-Rae, Byun, Hee Sun, Won, Minho, Park, Kyeong Ah, Kim, Jin Man, Choi, Byung Lyul, Lee, Hyunji, Hong, Jang Hee, Park, Jongsun, Seok, Jeong Ho, Kim, Dong Wook, Shong, Minho, Park, Seung-Kiel, Hur, Gang Min
Publicat 2008