Prediction of Acquired Taxane Resistance Using a Personalized Pathway-Based Machine Learning Method

Por Kim, Young Rae, Kim, Dongha, Kim, Sung Young
Publicado no Cancer Res Treat (2019)

Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1

Por Vikram, Ajit, Kim, Young-Rae, Kumar, Santosh, Li, Qiuxia, Kassan, Modar, Jacobs, Julia S., Irani, Kaikobad
Publicado no Nat Commun (2016)

Personalized Prediction of Acquired Resistance to EGFR-Targeted Inhibitors Using a Pathway-Based Machine Learning Approach

Por Kim, Young Rae, Kim, Yong Wan, Lee, Suh Eun, Yang, Hye Won, Kim, Sung Young
Publicado no Cancers (Basel) (2019)

Epigenetic upregulation of p66shc mediates low-density lipoprotein cholesterol-induced endothelial cell dysfunction

Por Kim, Young-Rae, Kim, Cuk-Seong, Naqvi, Asma, Kumar, Ajay, Kumar, Santosh, Hoffman, Timothy A., Irani, Kaikobad
Publicado em 2012

Redox Factor-1 Activates Endothelial SIRTUIN1 through Reduction of Conserved Cysteine Sulfhydryls in Its Deacetylase Domain

Por Jung, Saet-Byel, Kim, Cuk-Seong, Kim, Young-Rae, Naqvi, Asma, Yamamori, Tohru, Kumar, Santosh, Kumar, Ajay, Irani, Kaikobad
Publicado em 2013

MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1

Por Kassan, Modar, Vikram, Ajit, Li, Qiuxia, Kim, Young-Rae, Kumar, Santosh, Gabani, Mohanad, Liu, Jing, Jacobs, Julia S., Irani, Kaikobad
Publicado no Sci Rep (2017)

P66Shc-induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1

Por Li, Qiuxia, Kim, Young-Rae, Vikram, Ajit, Kumar, Santosh, Kassan, Modar, Gabani, Mohanad, Lee, Sang Ki, Jacobs, Julia S, Irani, Kaikobad
Publicado no Arterioscler Thromb Vasc Biol (2016)

Mulberry Fruit Extract Protects Pancreatic β-Cells against Hydrogen Peroxide-Induced Apoptosis via Antioxidative Activity

Por Lee, Jong Seok, Kim, Young Rae, Park, Jun Myoung, Ha, Suk-Jin, Kim, Young Eon, Baek, Nam In, Hong, Eock Kee
Publicado no Molecules (2014)

Canonical Wnt signaling induces vascular endothelial dysfunction via p66(Shc)-regulated reactive oxygen species

Por Vikram, Ajit, Kim, Young-Rae, Kumar, Santosh, Naqvi, Asma, Hoffman, Timothy A., Kumar, Ajay, Miller, Francis J., Kim, Cuk-Seong, Irani, Kaikobad
Publicado no Arterioscler Thromb Vasc Biol (2014)

Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice.

Por Gaddam, Ravinder Reddy, Kim, Young-Rae, Li, Quixia, Jacobs, Julia S, Gabani, Mohanad, Mishra, Akansha, Promes, Joseph A, Imai, Yumi, Irani, Kaikobad, Vikram, Ajit
Publicado no Biochem Biophys Res Commun (2020)

Sirtuin1-regulated lysine acetylation of p66Shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction

Por Kumar, Santosh, Kim, Young-Rae, Vikram, Ajit, Naqvi, Asma, Li, Qiuxia, Kassan, Modar, Kumar, Vikas, Bachschmid, Markus M., Jacobs, Julia S., Kumar, Ajay, Irani, Kaikobad
Publicado no Proc Natl Acad Sci U S A (2017)

Corrigendum: Sirtuin1 protects endothelial Caveolin-1 expression and preserves endothelial function via suppressing miR-204 and endoplasmic reticulum stress

Por Kassan, Modar, Vikram, Ajit, Kim, Young-Rae, Li, Qiuxia, Kassan, Adam, Patel, Hemal H., Kumar, Santosh, Gabani, Mohanad, Liu, Jing, Jacobs, Julia S., Irani, Kaikobad
Publicado no Sci Rep (2017)

MiR-204 regulates type 1 IP(3)R to control vascular smooth muscle cell contractility and blood pressure

Por Gabani, Mohanad, Liu, Jing, Ait-Aissa, Karima, Koval, Olha, Kim, Young-Rae, Castañeda, Diana, Vikram, Ajit, Jacobs, Julia S., Grumbach, Isabella, Trebak, Mohamed, Irani, Kaikobad, Kassan, Modar
Publicado no Cell Calcium (2019)

Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc

Por Kim, Cuk-Seong, Kim, Young-Rae, Naqvi, Asma, Kumar, Santosh, Hoffman, Timothy A., Jung, Saet-Byel, Kumar, Ajay, Jeon, Byeong-Hwa, McNamara, Dennis M., Irani, Kaikobad
Publicado em 2011

Long-term Activation of c-Jun N-terminal Kinase through Receptor Interacting Protein is Associated with DNA Damage-induced Cell Death

Por Seok, Jeong Ho, Park, Kyeong Ah, Byun, Hee Sun, Won, Minho, Shin, Sanghee, Choi, Byung-Lyul, Lee, Hyunji, Kim, Young-Rae, Hong, Jang Hee, Park, Jongsun, Hur, Gang Min
Publicado em 2008

Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice

Por Gaddam, Ravinder Reddy, Jacobsen, Veronica Peotta, Kim, Young-Rae, Gabani, Mohanad, Jacobs, Julia S., Dhuri, Karishma, Kumar, Santosh, Kassan, Modar, Li, Qiuxia, Bahal, Raman, Roghair, Robert, Irani, Kaikobad, Vikram, Ajit
Publicado no Sci Rep (2020)

A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expression

Por Naqvi, Asma, Hoffman, Timothy A., DeRicco, Jeremy, Kumar, Ajay, Kim, Cuk-Seong, Jung, Saet-Byel, Yamamori, Tohru, Kim, Young-Rae, Mehdi, Fardeen, Kumar, Santosh, Rankinen, Tuomo, Ravussin, Eric, Irani, Kaikobad
Publicado em 2010

Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase

Por Byun, Hee Sun, Won, Minho, Park, Kyeong Ah, Kim, Young-Rae, Choi, Byung Lyul, Lee, Hyunji, Hong, Jang Hee, Piao, Longzhen, Park, Jongsun, Kim, Jin Man, Kweon, Gi Ryang, Kang, Sung Hyun, Han, Jin, Hur, Gang Min
Publicado em 2008

Two-terminal floating-gate memory with van der Waals heterostructures for ultrahigh on/off ratio

Por Vu, Quoc An, Shin, Yong Seon, Kim, Young Rae, Nguyen, Van Luan, Kang, Won Tae, Kim, Hyun, Luong, Dinh Hoa, Lee, Il Min, Lee, Kiyoung, Ko, Dong-Su, Heo, Jinseong, Park, Seongjun, Lee, Young Hee, Yu, Woo Jong
Publicado no Nat Commun (2016)

Modulatory role of phospholipase D in the activation of signal transducer and activator of transcription (STAT)-3 by thyroid oncogenic kinase RET/PTC

Por Kim, Young-Rae, Byun, Hee Sun, Won, Minho, Park, Kyeong Ah, Kim, Jin Man, Choi, Byung Lyul, Lee, Hyunji, Hong, Jang Hee, Park, Jongsun, Seok, Jeong Ho, Kim, Dong Wook, Shong, Minho, Park, Seung-Kiel, Hur, Gang Min
Publicado em 2008