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P66Shc-induced MicroRNA-34a Causes Diabetic Endothelial Dysfunction by Downregulating Sirtuin1
OBJECTIVE: Diabetes mellitus causes vascular endothelial dysfunction and alters vascular microRNA expression. We investigated if endothelial microRNA-34a (miR-34a) leads to diabetic vascular dysfunction by targeting endothelial Sirtuin1 (Sirt1), and asked if the oxidative stress protein p66Shc gover...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293179/ https://ncbi.nlm.nih.gov/pubmed/27789474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308321 |
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