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MicroRNA-204 promotes vascular endoplasmic reticulum stress and endothelial dysfunction by targeting Sirtuin1

Endoplasmic reticulum (ER) stress has been implicated in vascular endothelial dysfunction of obesity, diabetes, and hypertension. MicroRNAs play an important role in regulating ER stress. Here we show that microRNA-204 (miR-204) promotes vascular ER stress and endothelial dysfunction by targeting th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kassan, Modar, Vikram, Ajit, Li, Qiuxia, Kim, Young-Rae, Kumar, Santosh, Gabani, Mohanad, Liu, Jing, Jacobs, Julia S., Irani, Kaikobad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571183/
https://ncbi.nlm.nih.gov/pubmed/28839162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06721-y
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