Prevention of TNF-induced necrotic cell death by rottlerin through a Nox1 NADPH oxidase

Previous studies have demonstrated that rottlerin, a specific PKCδ inhibitor, potentiates death receptormediated apoptosis through a cytochrome c-dependent or -independent pathway. However, its ability to regulate necrotic cell death, as well as the underlying mechanism, remains unknown. We found th...

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Detalhes bibliográficos
Main Authors: Byun, Hee Sun, Won, Minho, Park, Kyeong Ah, Kim, Young-Rae, Choi, Byung Lyul, Lee, Hyunji, Hong, Jang Hee, Piao, Longzhen, Park, Jongsun, Kim, Jin Man, Kweon, Gi Ryang, Kang, Sung Hyun, Han, Jin, Hur, Gang Min
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Medical Biochemistry and Molecular Biology 2008
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679309/
https://ncbi.nlm.nih.gov/pubmed/18446057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2008.40.2.186
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