Relation of atherogenic lipoproteins with estimated glomerular filtration rate decline: a longitudinal study

Por Lin, Jennie, Khetarpal, Sumeet A., Terembula, Karen, Reilly, Muredach P., Wilson, F. Perry
Publicado no BMC Nephrol (2015)

Plasma ApoC-III Levels, Triglycerides, and Coronary Artery Calcification in Type 2 Diabetics

Por Qamar, Arman, Khetarpal, Sumeet A., Khera, Amit V., Qasim, Atif, Rader, Daniel J., Reilly, Muredach P.
Publicado no Arterioscler Thromb Vasc Biol (2015)

A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation

Por Goth, Christoffer K., Halim, Adnan, Khetarpal, Sumeet A., Rader, Daniel J., Clausen, Henrik, Schjoldager, Katrine T.-B. G.
Publicado no Proc Natl Acad Sci U S A (2015)

The Effects of Apolipoprotein F Deficiency on High Density Lipoprotein Cholesterol Metabolism in Mice

Por Lagor, William R., Fields, David W., Khetarpal, Sumeet A., Kumaravel, Arthi, Lin, Wen, Weintraub, Nathaniel, Wu, Kaijin, Hamm-Alvarez, Sarah F., Drazul-Schrader, Denise, de la Llera-Moya, Margarita, Rothblat, George H., Rader, Daniel J.
Publicado em 2012

Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol

Por Khetarpal, Sumeet A., Edmondson, Andrew C., Raghavan, Avanthi, Neeli, Hemanth, Jin, Weijun, Badellino, Karen O., Demissie, Serkalem, Manning, Alisa K., DerOhannessian, Stephanie L., Wolfe, Megan L., Cupples, L. Adrienne, Li, Mingyao, Kathiresan, Sekar, Rader, Daniel J.
Publicado em 2011

Polygenic determinants in extremes of high-density lipoprotein cholesterol

Por Dron, Jacqueline S., Wang, Jian, Low-Kam, Cécile, Khetarpal, Sumeet A., Robinson, John F., McIntyre, Adam D., Ban, Matthew R., Cao, Henian, Rhainds, David, Dubé, Marie-Pierre, Rader, Daniel J., Lettre, Guillaume, Tardif, Jean-Claude, Hegele, Robert A.
Publicado no J Lipid Res (2017)

Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans

Por Edmondson, Andrew C., Brown, Robert J., Kathiresan, Sekar, Cupples, L. Adrienne, Demissie, Serkalem, Manning, Alisa Knodle, Jensen, Majken K., Rimm, Eric B., Wang, Jian, Rodrigues, Amrith, Bamba, Vaneeta, Khetarpal, Sumeet A., Wolfe, Megan L., DerOhannessian, Stephanie, Li, Mingyao, Reilly, Muredach P., Aberle, Jens, Evans, David, Hegele, Robert A., Rader, Daniel J.
Publicado em 2009

A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

Por Khetarpal, Sumeet A, Zeng, Xuemei, Millar, John S, Vitali, Cecilia, Somasundara, Amritha Varshini Hanasoge, Zanoni, Paolo, Landro, James A, Barucci, Nicole, Zavadoski, William J, Sun, Zhiyuan, de Haard, Hans, Toth, Ildikó V, Peloso, Gina M, Natarajan, Pradeep, Cuchel, Marina, Lund-Katz, Sissel, Phillips, Michael C, Tall, Alan R, Kathiresan, Sekar, DaSilva-Jardine, Paul, Yates, Nathan A, Rader, Daniel J
Publicado no Nat Med (2017)

Loss of function of GALNT2 lowers high density lipoproteins in humans, nonhuman primates, and rodents

Por Khetarpal, Sumeet A., Schjoldager, Katrine T., Christoffersen, Christina, Raghavan, Avanthi, Edmondson, Andrew C., Reutter, Heiko M., Ahmed, Bouhouche, Ouzzani, R, Peloso, Gina M., Vitali, Cecilia, Zhao, Wei, Somasundara, Amritha Varshini Hanasoge, Millar, John S., Park, YoSon, Fernando, Gayani, Livanov, Valentin, Choi, Seungbum, Noé, Eric, Patel, Pritesh, Ho, Siew Peng, Kirchgessner, Todd G., Wandall, Hans H., Hansen, Lars, Bennett, Eric P., Vakhrushev, Sergey Y., Saleheen, Danish, Kathiresan, Sekar, Brown, Christopher D., Jamra, Rami Abou, LeGuern, Eric, Clausen, Henrik, Rader, Daniel J.
Publicado no Cell Metab (2016)

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

Por Zanoni, Paolo, Khetarpal, Sumeet A., Larach, Daniel B., Hancock-Cerutti, William F., Millar, John S., Cuchel, Marina, DerOhannessian, Stephanie, Kontush, Anatol, Surendran, Praveen, Saleheen, Danish, Trompet, Stella, Jukema, J. Wouter, De Craen, Anton, Deloukas, Panos, Sattar, Naveed, Ford, Ian, Packard, Chris, Majumder, Abdullah al Shafi, Alam, Dewan S., Di Angelantonio, Emanuele, Abecasis, Goncalo, Chowdhury, Rajiv, Erdmann, Jeanette, Nordestgaard, Børge G., Nielsen, Sune F., Tybjærg-Hansen, Anne, Schmidt, Ruth Frikke, Kuulasmaa, Kari, Liu, Dajiang J., Perola, Markus, Blankenberg, Stefan, Salomaa, Veikko, Männistö, Satu, Amouyel, Philippe, Arveiler, Dominique, Ferrieres, Jean, Müller-Nurasyid, Martina, Ferrario, Marco, Kee, Frank, Willer, Cristen J., Samani, Nilesh, Schunkert, Heribert, Butterworth, Adam S., Howson, Joanna M. M., Peloso, Gina M., Stitziel, Nathan O., Danesh, John, Kathiresan, Sekar, Rader, Daniel J.
Publicado no Science (2016)

Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

Por Peloso, Gina M., Auer, Paul L., Bis, Joshua C., Voorman, Arend, Morrison, Alanna C., Stitziel, Nathan O., Brody, Jennifer A., Khetarpal, Sumeet A., Crosby, Jacy R., Fornage, Myriam, Isaacs, Aaron, Jakobsdottir, Johanna, Feitosa, Mary F., Davies, Gail, Huffman, Jennifer E., Manichaikul, Ani, Davis, Brian, Lohman, Kurt, Joon, Aron Y., Smith, Albert V., Grove, Megan L., Zanoni, Paolo, Redon, Valeska, Demissie, Serkalem, Lawson, Kim, Peters, Ulrike, Carlson, Christopher, Jackson, Rebecca D., Ryckman, Kelli K., Mackey, Rachel H., Robinson, Jennifer G., Siscovick, David S., Schreiner, Pamela J., Mychaleckyj, Josyf C., Pankow, James S., Hofman, Albert, Uitterlinden, Andre G., Harris, Tamara B., Taylor, Kent D., Stafford, Jeanette M., Reynolds, Lindsay M., Marioni, Riccardo E., Dehghan, Abbas, Franco, Oscar H., Patel, Aniruddh P., Lu, Yingchang, Hindy, George, Gottesman, Omri, Bottinger, Erwin P., Melander, Olle, Orho-Melander, Marju, Loos, Ruth J.F., Duga, Stefano, Merlini, Piera Angelica, Farrall, Martin, Goel, Anuj, Asselta, Rosanna, Girelli, Domenico, Martinelli, Nicola, Shah, Svati H., Kraus, William E., Li, Mingyao, Rader, Daniel J., Reilly, Muredach P., McPherson, Ruth, Watkins, Hugh, Ardissino, Diego, Zhang, Qunyuan, Wang, Judy, Tsai, Michael Y., Taylor, Herman A., Correa, Adolfo, Griswold, Michael E., Lange, Leslie A., Starr, John M., Rudan, Igor, Eiriksdottir, Gudny, Launer, Lenore J., Ordovas, Jose M., Levy, Daniel, Chen, Y.-D. Ida, Reiner, Alexander P., Hayward, Caroline, Polasek, Ozren, Deary, Ian J., Borecki, Ingrid B., Liu, Yongmei, Gudnason, Vilmundur, Wilson, James G., van Duijn, Cornelia M., Kooperberg, Charles, Rich, Stephen S., Psaty, Bruce M., Rotter, Jerome I., O’Donnell, Christopher J., Rice, Kenneth, Boerwinkle, Eric, Kathiresan, Sekar, Cupples, L. Adrienne
Publicado em 2014