Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol

Genome-wide association studies (GWAS) have successfully identified loci associated with quantitative traits, such as blood lipids. Deep resequencing studies are being utilized to catalogue the allelic spectrum at GWAS loci. The goal of these studies is to identify causative variants and missing her...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Khetarpal, Sumeet A., Edmondson, Andrew C., Raghavan, Avanthi, Neeli, Hemanth, Jin, Weijun, Badellino, Karen O., Demissie, Serkalem, Manning, Alisa K., DerOhannessian, Stephanie L., Wolfe, Megan L., Cupples, L. Adrienne, Li, Mingyao, Kathiresan, Sekar, Rader, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234219/
https://ncbi.nlm.nih.gov/pubmed/22174694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002393
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge