A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis

Human endothelial lipase (EL) is a member of a family of lipases and phospholipases that are involved in the metabolism of plasma lipoproteins. EL displays a preference to hydrolyze lipids in HDL. We report here that a naturally occurring low frequency coding variant in the EL gene (LIPG), glycine-2...

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Detalhes bibliográficos
Main Authors: Brown, Robert J., Edmondson, Andrew C., Griffon, Nathalie, Hill, Theophelus B., Fuki, Ilia V., Badellino, Karen O., Li, Mingyao, Wolfe, Megan L., Reilly, Muredach P., Rader, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Patient-Oriented and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724790/
https://ncbi.nlm.nih.gov/pubmed/19411705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P900020-JLR200
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