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Endothelial Lipase Concentrations Are Increased in Metabolic Syndrome and Associated with Coronary Atherosclerosis

BACKGROUND: Endothelial lipase (EL), a new member of the lipase family, has been shown to modulate high-density lipoprotein (HDL-C) metabolism and atherosclerosis in mouse models. We hypothesized that EL concentrations would be associated with decreased HDL-C and increased atherosclerosis in humans....

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Autors principals: Badellino, Karen O, Wolfe, Megan L, Reilly, Muredach P, Rader, Daniel J
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316064/
https://ncbi.nlm.nih.gov/pubmed/16354105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0030022
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