Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians

OBJECTIVE: Resistin causes insulin resistance and diabetes in mice whereas in humans it is linked to inflammation and atherosclerosis. Few human genetic studies of resistin in inflammation and atherosclerosis have been performed. We hypothesized that the −420C>G putative gain-of-function resistin...

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Hlavní autoři: Qasim, Atif N., Metkus, Thomas S., Tadesse, Mahlet, Lehrke, Michael, Restine, Stephanie, Wolfe, Megan L., Hannenhalli, Sridhar, Cappola, Thomas, Rader, Daniel J., Reilly, Muredach P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108432/
https://ncbi.nlm.nih.gov/pubmed/18710472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2265.2008.03375.x
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