Dual-specificity MAP kinase phosphatases (MKPs): Shaping the outcome of MAP kinase signalling

Por Caunt, Christopher J, Keyse, Stephen M
Publicado em 2013

The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)

Por Kidger, Andrew M., Keyse, Stephen M.
Publicado no Semin Cell Dev Biol (2016)

Specific Inactivation and Nuclear Anchoring of Extracellular Signal-Regulated Kinase 2 by the Inducible Dual-Specificity Protein Phosphatase DUSP5

Por Mandl, Margret, Slack, David N., Keyse, Stephen M.
Publicado em 2005

Transcriptional Induction of MKP-1 in Response to Stress Is Associated with Histone H3 Phosphorylation-Acetylation

Por Li, Ji, Gorospe, Myriam, Hutter, Dorothy, Barnes, Janice, Keyse, Stephen M., Liu, Yusen
Publicado em 2001

Both Binding and Activation of p38 Mitogen-Activated Protein Kinase (MAPK) Play Essential Roles in Regulation of the Nucleocytoplasmic Distribution of MAPK-Activated Protein Kinase...

Por Seternes, Ole Morten, Johansen, Bjarne, Hegge, Beate, Johannessen, Mona, Keyse, Stephen M., Moens, Ugo
Publicado em 2002

Docking of PRAK/MK5 to the Atypical MAPKs ERK3 and ERK4 Defines a Novel MAPK Interaction Motif

Por Åberg, Espen, Torgersen, Knut Martin, Johansen, Bjarne, Keyse, Stephen M., Perander, Maria, Seternes, Ole-Morten
Publicado em 2009

Regulation of Caenorhabditis elegans p53/CEP-1–Dependent Germ Cell Apoptosis by Ras/MAPK Signaling

Por Rutkowski, Rachael, Dickinson, Robin, Stewart, Graeme, Craig, Ashley, Schimpl, Marianne, Keyse, Stephen M., Gartner, Anton
Publicado em 2011

Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation

Por Staples, Christopher J., Owens, David M., Maier, Jana V., Cato, Andrew C. B., Keyse, Stephen M.
Publicado em 2010

Cross-talk between the p38α and JNK MAPK pathways mediated by MAP kinase phosphatase-1 determines cellular sensitivity to UV radiation.

Por Staples, Christopher J., Owens, David M., Maier, Jana V., Cato, Andrew C. B., Keyse, Stephen M.
Publicado em 2011

Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase.

Por Dickinson, Robin J, Williams, David J, Slack, David N, Williamson, Jill, Seternes, Ole-Morten, Keyse, Stephen M
Publicado em 2002

The Dual-Specificity Protein Phosphatase DUSP9/MKP-4 Is Essential for Placental Function but Is Not Required for Normal Embryonic Development

Por Christie, Graham R., Williams, David J., MacIsaac, Fiona, Dickinson, Robin J., Rosewell, Ian, Keyse, Stephen M.
Publicado em 2005

Distinct Docking Mechanisms Mediate Interactions between the Msg5 Phosphatase and Mating or Cell Integrity Mitogen-activated Protein Kinases (MAPKs) in Saccharomyces cerevisiae

Por Palacios, Lorena, Dickinson, Robin J., Sacristán-Reviriego, Almudena, Didmon, Mark P., Marín, María José, Martín, Humberto, Keyse, Stephen M., Molina, María
Publicado em 2011

Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

Por Seternes, Ole-Morten, Mikalsen, Theresa, Johansen, Bjarne, Michaelsen, Espen, Armstrong, Chris G, Morrice, Nick A, Turgeon, Benjamin, Meloche, Sylvain, Moens, Ugo, Keyse, Stephen M
Publicado em 2004

Activation of MK5/PRAK by the atypical MAP kinase ERK3 defines a novel signal transduction pathway

Por Seternes, Ole-Morten, Mikalsen, Theresa, Johansen, Bjarne, Michaelsen, Espen, Armstrong, Chris G, Morrice, Nick A, Turgeon, Benjamin, Meloche, Sylvain, Moens, Ugo, Keyse, Stephen M
Publicado em 2005

Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2

Por Perander, Maria, Al-Mahdi, Rania, Jensen, Thomas C., Nunn, Jennifer A. L., Kildalsen, Hanne, Johansen, Bjarne, Gabrielsen, Mads, Keyse, Stephen M., Seternes, Ole-Morten
Publicado no Sci Rep (2017)

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Por Kidger, Andrew M., Rushworth, Linda K., Stellzig, Julia, Davidson, Jane, Bryant, Christopher J., Bayley, Cassidy, Caddye, Edward, Rogers, Tim, Keyse, Stephen M., Caunt, Christopher J.
Publicado no Proc Natl Acad Sci U S A (2017)

Phosphorylation of the Kinase Interaction Motif in Mitogen-activated Protein (MAP) Kinase Phosphatase-4 Mediates Cross-talk between Protein Kinase A and MAP Kinase Signaling Pathwa...

Por Dickinson, Robin J., Delavaine, Laurent, Cejudo-Marín, Rocío, Stewart, Graeme, Staples, Christopher J., Didmon, Mark P., Trinidad, Antonio Garcia, Alonso, Andrés, Pulido, Rafael, Keyse, Stephen M.
Publicado em 2011

Gene Trap Mice Reveal an Essential Function of Dual Specificity Phosphatase Dusp16/MKP-7 in Perinatal Survival and Regulation of Toll-like Receptor (TLR)-induced Cytokine Productio...

Por Niedzielska, Magdalena, Bodendorfer, Barbara, Münch, Sandra, Eichner, Alexander, Derigs, Marcus, da Costa, Olivia, Schweizer, Astrid, Neff, Frauke, Nitschke, Lars, Sparwasser, Tim, Keyse, Stephen M., Lang, Roland
Publicado em 2014

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter

Por Ekerot, Maria, Stavridis, Marios P., Delavaine, Laurent, Mitchell, Michael P., Staples, Christopher, Owens, David M., Keenan, Iain D., Dickinson, Robin J., Storey, Kate G., Keyse, Stephen M.
Publicado em 2008

Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRas(Q61L))-driven SerpinB2 expression

Por Rushworth, Linda K., Kidger, Andrew M., Delavaine, Laurent, Stewart, Graeme, van Schelven, Susanne, Davidson, Jane, Bryant, Christopher J., Caddye, Edward, East, Philip, Caunt, Christopher J., Keyse, Stephen M.
Publicado no Proc Natl Acad Sci U S A (2014)