Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2

The atypical MAP kinases ERK3 and ERK4 are activated by phosphorylation of a serine residue lying within the activation loop signature sequence S-E-G. However, the regulation of ERK3 and ERK4 phosphorylation and activity is poorly understood. Here we report that the inducible nuclear dual-specificit...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Perander, Maria, Al-Mahdi, Rania, Jensen, Thomas C., Nunn, Jennifer A. L., Kildalsen, Hanne, Johansen, Bjarne, Gabrielsen, Mads, Keyse, Stephen M., Seternes, Ole-Morten
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333157/
https://ncbi.nlm.nih.gov/pubmed/28252035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43471
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