Specific Inactivation and Nuclear Anchoring of Extracellular Signal-Regulated Kinase 2 by the Inducible Dual-Specificity Protein Phosphatase DUSP5

The mechanisms which determine the nuclear accumulation and inactivation of the extracellular signal-regulated kinase 1 (ERK1) or ERK2 mitogen-activated protein (MAP) kinases are poorly understood. Here we demonstrate that DUSP5, an inducible nuclear phosphatase, interacts specifically with ERK2 via...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Mandl, Margret, Slack, David N., Keyse, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2005
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15713638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.5.1830-1845.2005
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi