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The Dual-specificity Phosphatase DUSP14 Negatively Regulates Tumor Necrosis Factor- and Interleukin-1-induced Nuclear Factor-κB Activation by Dephosphorylating the Protein Kinase TAK1

The transcription factor NF-κB is critically involved in the inflammatory response triggered by the proinflammatory cytokines TNF and IL-1. Various studies have demonstrated that activation of TAK1 (TGF-β-activated kinase 1) is an essential step in TNF- and IL-1-induced NF-κB activation pathways. In...

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Detaylı Bibliyografya
Asıl Yazarlar: Zheng, Hao, Li, Qi, Chen, Rui, Zhang, Jing, Ran, Yong, He, Xiao, Li, Shu, Shu, Hong-Bing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543031/
https://ncbi.nlm.nih.gov/pubmed/23229544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412643
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