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The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)

Dual-specificity MAP kinase (MAPK) phosphatases (MKPs or DUSPs) are well-established negative regulators of MAPK signalling in mammalian cells and tissues. By virtue of their differential subcellular localisation and ability to specifically recognise, dephosphorylate and inactivate different MAPK is...

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Detalles Bibliográficos
Publicado en:Semin Cell Dev Biol
Main Authors: Kidger, Andrew M., Keyse, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056954/
https://ncbi.nlm.nih.gov/pubmed/26791049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.01.009
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