Assessment of the relative in vivo potency of the hydroxylated metabolite of darifenacin in its ability to decrease salivary flow using pooled population pharmacokinetic–pharmacody...

Por Kerbusch, Thomas, Milligan, Peter A, Karlsson, Mats O
Publicado em 2004

Modeling and Simulation at the Interface of Nonclinical and Early Clinical Drug Development

Por Visser, S A G, Manolis, E, Danhof, M, Kerbusch, T
Publicado em 2013

Population pharmacokinetic modelling of darifenacin and its hydroxylated metabolite using pooled data, incorporating saturable first-pass metabolism, CYP2D6 genotype and formulatio...

Por Kerbusch, Thomas, Wählby, Ulrika, Milligan, Peter A, Karlsson, Mats O
Publicado em 2003

Prediction of Clinical Irrelevance of PK Differences in Atorvastatin Using PK/PD Models Derived From Literature-Based Meta-Analyses

Por Vargo, R, Adewale, A, Behm, M O, Mandema, J, Kerbusch, T
Publicado em 2014

Population pharmacokinetic–pharmacodynamic analysis for sugammadex-mediated reversal of rocuronium-induced neuromuscular blockade

Por Kleijn, Huub J, Zollinger, Daniel P, van den Heuvel, Michiel W, Kerbusch, Thomas
Publicado em 2011

Implementation of Quantitative and Systems Pharmacology in Large Pharma

Por Visser, S A G, de Alwis, D P, Kerbusch, T, Stone, J A, Allerheiligen, S R B
Publicado no CPT Pharmacometrics Syst Pharmacol (2014)

Anisotropic metal growth on phospholipid nanodiscs via lipid bilayer expansion

Por Oertel, Jana, Keller, Adrian, Prinz, Julia, Schreiber, Benjamin, Hübner, René, Kerbusch, Jochen, Bald, Ilko, Fahmy, Karim
Publicado no Sci Rep (2016)

Population Pharmacokinetics and Pharmacodynamics of Bezlotoxumab in Adults with Primary and Recurrent Clostridium difficile Infection

Por Yee, Ka Lai, Kleijn, Huub Jan, Kerbusch, Thomas, Matthews, Randolph P., Dorr, Mary Beth, Garey, Kevin W., Wrishko, Rebecca E.
Publicado no Antimicrob Agents Chemother (2019)

Assessment of the effects of immunogenicity on the pharmacokinetics, efficacy and safety of tildrakizumab

Por Kimball, A.B., Kerbusch, T., van Aarle, F., Kulkarni, P., Li, Q., Blauvelt, A., Papp, K.A., Reich, K., Montgomery, D.
Publicado no Br J Dermatol (2019)

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM

Por Kerbusch, T, Huitema, A D R, Ouwerkerk, J, Keizer, H J, Mathôt, R A A, Schellens, J H M, Beijnen, J H
Publicado em 2000

Light‐Induced Switching of Tunable Single‐Molecule Junctions

Por Sendler, Torsten, Luka‐Guth, Katharina, Wieser, Matthias, Lokamani, Wolf, Jannic, Helm, Manfred, Gemming, Sibylle, Kerbusch, Jochen, Scheer, Elke, Huhn, Thomas, Erbe, Artur
Publicado no Adv Sci (Weinh) (2015)

Molecular Electronics: Light‐Induced Switching of Tunable Single‐Molecule Junctions (Adv. Sci. 5/2015)

Por Sendler, Torsten, Luka‐Guth, Katharina, Wieser, Matthias, Lokamani, Wolf, Jannic, Helm, Manfred, Gemming, Sibylle, Kerbusch, Jochen, Scheer, Elke, Huhn, Thomas, Erbe, Artur
Publicado no Adv Sci (Weinh) (2015)

Maternal–Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing

Por Lommerse, Jos, Clarke, Diana, Kerbusch, Thomas, Merdjan, Henri, Witjes, Han, Teppler, Hedy, Mirochnick, Mark, Acosta, Edward P., Wenning, Larissa, Nachman, Sharon, Chain, Anne
Publicado no CPT Pharmacometrics Syst Pharmacol (2019)

Pooled population pharmacokinetic model of imipenem in plasma and the lung epithelial lining fluid

Por van Hasselt, J. G. Coen, Rizk, Matthew L., Lala, Mallika, Chavez‐Eng, Cynthia, Visser, Sandra A. G., Kerbusch, Thomas, Danhof, Meindert, Rao, Gauri, van der Graaf, Piet H.
Publicado no Br J Clin Pharmacol (2016)

Phase I and pharmacokinetic study of the combination of topotecan and ifosfamide administered intravenously every 3 weeks

Por Kerbusch, T, Groenewegen, G, Mathôt, R A A, Herben, V M M, ten Bokkel Huinink, W W, Swart, M, Ambaum, B, Rosing, H, Jansen, S, Voest, E E, Beijnen, J H, Schellens, J H M
Publicado em 2004

Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation

Por Marshall, SF, Burghaus, R, Cosson, V, Cheung, SYA, Chenel, M, DellaPasqua, O, Frey, N, Hamrén, B, Harnisch, L, Ivanow, F, Kerbusch, T, Lippert, J, Milligan, PA, Rohou, S, Staab, A, Steimer, JL, Tornøe, C, Visser, SAG
Publicado no CPT Pharmacometrics Syst Pharmacol (2016)