Population pharmacokinetic–pharmacodynamic analysis for sugammadex-mediated reversal of rocuronium-induced neuromuscular blockade

AIMS: An integrated population pharmacokinetic–pharmacodynamic model was developed with the following aims: to simultaneously describe pharmacokinetic behaviour of sugammadex and rocuronium; to establish the pharmacokinetic–pharmacodynamic model for rocuronium-induced neuromuscular blockade and reve...

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Detalhes bibliográficos
Main Authors: Kleijn, Huub J, Zollinger, Daniel P, van den Heuvel, Michiel W, Kerbusch, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Pharmacokinetic Dynamic Relationships
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175511/
https://ncbi.nlm.nih.gov/pubmed/21535448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04000.x
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