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Population pharmacokinetic–pharmacodynamic analysis for sugammadex-mediated reversal of rocuronium-induced neuromuscular blockade

AIMS: An integrated population pharmacokinetic–pharmacodynamic model was developed with the following aims: to simultaneously describe pharmacokinetic behaviour of sugammadex and rocuronium; to establish the pharmacokinetic–pharmacodynamic model for rocuronium-induced neuromuscular blockade and reve...

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Main Authors: Kleijn, Huub J, Zollinger, Daniel P, van den Heuvel, Michiel W, Kerbusch, Thomas
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175511/
https://ncbi.nlm.nih.gov/pubmed/21535448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04000.x
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