Defining success with cellular therapeutics: the current landscape for clinical end point and toxicity analysis

Por Kean, Leslie S.
Publicado no Blood (2018)

Advances in Targeting Co-inhibitory and Co-stimulatory Pathways in Transplantation Settings: The Yin to the Yang of Cancer Immunotherapy

Por Kean, Leslie S., Turka, Laurence A., Blazar, Bruce R.
Publicado no Immunol Rev (2017)

Building a Safer and Faster CAR: Seatbelts, Airbags and CRISPR

Por Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel
Publicado no Biol Blood Marrow Transplant (2017)

Pluripotent Stem Cells: Immune to the Immune system?

Por Pearl, Jeremy I., Kean, Leslie S., Davis, Mark M., Wu, Joseph C.
Publicado em 2012

Persistence of Virus Reservoirs in ART-Treated SHIV-Infected Rhesus Macaques after Autologous Hematopoietic Stem Cell Transplant

Por Mavigner, Maud, Watkins, Benjamin, Lawson, Benton, Lee, S. Thera, Chahroudi, Ann, Kean, Leslie, Silvestri, Guido
Publicado em 2014

Use of Alefacept for Preconditioning in Multiply Transfused Pediatric Patients with Nonmalignant Diseases

Por Stenger, Elizabeth O., Chiang, Kuang-Yueh, Haight, Ann, Qayed, Muna, Kean, Leslie, Horan, John
Publicado no Biol Blood Marrow Transplant (2015)

Plasma Membrane Translocation of Fluorescent-labeled Phosphatidylethanolamine Is Controlled by Transcription Regulators, PDR1 and PDR3

Por Kean, Leslie S., Grant, Althea M., Angeletti, Cesar, Mahé, Yannick, Kuchler, Karl, Fuller, Robert S., Nichols, J. Wylie
Publicado em 1997

A Canine Model of Chronic Graft-vs.-Host Disease

Por Graves, Scott S., Rezvani, Andrew, Sale, George, Stone, Diane, Parker, Maura, Rosinski, Steven, Spector, Michele, Swearingen, Bruce, Kean, Leslie, Storb, Rainer
Publicado no Biol Blood Marrow Transplant (2016)

Red Blood Cell Transfusions Are Associated with HLA Class I but not H-Y Alloantibodies in Children with Sickle Cell Disease

Por Nickel, Robert S., Hendrickson, Jeanne E., Yee, Marianne M., Bray, Robert A., Gebel, Howard M., Kean, Leslie S., Miklos, David B., Horan, John T.
Publicado no Br J Haematol (2015)

Viewing Transplantation Immunology Through Today’s Lens: New Models, New Imaging, and New Insights

Por Huang, Alex Y., Haining, W. Nicholas, Barkauskas, Deborah S., Myers, Jay T., Petrosiute, Agne, Garrett, Aneesah P., Singh, Karnail, Cooke, Kenneth R., Kean, Leslie S.
Publicado no Biol Blood Marrow Transplant (2012)

Immune parameter analysis of children with sickle cell disease on hydroxycarbamide or chronic transfusion therapy

Por Nickel, Robert S., Osunkwo, Ifeyinwa, Garrett, Aneesah, Robertson, Jennifer, Archer, David R., Promislow, Daniel E.L., Horan, John T., Hendrickson, Jeanne E., Kean, Leslie S.
Publicado no Br J Haematol (2015)

Expanded Non-human Primate Tregs Exhibit A Unique Gene Expression Signature and Potently Downregulate Allo-immune Responses

Por Anderson, Alan, Martens, Christine, Hendrix, Rose, Stempora, Linda, Miller, Wes, Hamby, Kelly, Russell, Maria, Strobert, Elizabeth, Blazar, Bruce R., Pearson, Thomas C., Larsen, Christian P., Kean, Leslie S.
Publicado em 2008

Alloimmunization to transfused HOD RBCs is not increased in mice with sickle cell disease

Por Hendrickson, Jeanne E, Hod, Eldad A., Perry, Jennifer R., Chappa, Prasanthi, Adisa, Olufolake, Kean, Leslie S., Ofori-Acquah, Solomon F., Archer, David R., Spitalnik, Steven L., Zimring, James C.
Publicado em 2011

Significant mobilization of both conventional and regulatory T cells with AMD3100

Por Kean, Leslie S., Sen, Sharon, Onabajo, Olusegun, Singh, Karnail, Robertson, Jennifer, Stempora, Linda, Bonifacino, Aylin C., Metzger, Mark E., Promislow, Daniel E. L., Mattapallil, Joseph J., Donahue, Robert E.
Publicado em 2011

Preclinical testing of anti-human CD28 Fab’ antibody in a novel nonhuman primate (NHP) small animal rodent model of xenogenic graft-versus-host disease (GVHD)

Por Hippen, Keli L., Watkins, Benjamin, Tkachev, Victor, Lemire, Amanda M., Lehnen, Charles, Riddle, Megan J., Singh, Karnail, Panoskaltsis-Mortari, Angela, Vanhove, Bernard, Tolar, Jakub, Kean, Leslie S., Blazar, Bruce R.
Publicado no Transplantation (2016)

Resource Brief: The National Non-Human Primate DNA Bank

Por Ferguson, Betsy, Capitanio, John, Folks, Thomas, Hotchkiss, Charlotte, Johnson, Zachary, Kean, Leslie, Kubisch, H. Michael, Lank, Simon, Lyons, Leslie, Miller, Gregory M., Nylander, John, O'Connor, David, Vallender, Eric J., Wiseman, Roger
Publicado em 2009

Heterologous Immunity Triggered by a Single, Latent Virus in Mus musculus: Combined Costimulation- and Adhesion- Blockade Decrease Rejection

Por Beus, Jonathan M., Hashmi, Salila S., Selvaraj, Saranya A., Duan, Danxia, Stempora, Linda L., Monday, Stephanie A., Cheeseman, Jennifer A., Hamby, Kelly M., Speck, Samuel H., Larsen, Christian P., Kirk, Allan D., Kean, Leslie S.
Publicado em 2013

Renal Transplantation Using Belatacept Without Maintenance Steroids or Calcineurin Inhibitors

Por Kirk, Allan D., Guasch, Antonio, Xu, He, Cheeseman, Jennifer, Mead, Sue I., Ghali, Ada, Mehta, Aneesh K., Wu, Dona, Gebel, Howard, Bray, Robert, Horan, John, Kean, Leslie S., Larsen, Christian P., Pearson, Thomas C.
Publicado no Am J Transplant (2014)

An MHC-defined primate model reveals significant rejection of bone marrow after mixed-chimerism induction despite full MHC matching

Por Larsen, Christian P., Page, Andrew, Linzie, Kelly Hamby, Russell, Maria, Deane, Taylor, Stempora, Linda, Strobert, Elizabeth, Penedo, Maria Cecilia T., Ward, Thea, Wiseman, Roger, O'Connor, David, Miller, Weston, Sen, Sharon, Singh, Karnail, Kean, Leslie S.
Publicado em 2010

CD40 Blockade Combines with CTLA4Ig and Sirolimus To Produce Mixed Chimerism in an MHC-defined Rhesus Macaque Transplant Model

Por Page, Andrew, Srinivasan, Swetha, Singh, Karnail, Russell, Maria, Hamby, Kelly, Deane, Taylor, Sen, Sharon, Stempora, Linda, Leopardi, Frank, Price, Andrew A., Strobert, Elizabeth, Reimann, Keith A., Kirk, Allan D., Larsen, Christian P., Kean, Leslie S.
Publicado em 2011