Expanded Non-human Primate Tregs Exhibit A Unique Gene Expression Signature and Potently Downregulate Allo-immune Responses

We have established two complementary strategies for purifying naturally occurring regulatory T cells (Tregs) from rhesus macaques in quantities which would be sufficient for use as an in vivo cellular therapeutic. The first identified Tregs based on their being CD4+/CD25(bright). The second incorpo...

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Detalhes bibliográficos
Main Authors: Anderson, Alan, Martens, Christine, Hendrix, Rose, Stempora, Linda, Miller, Wes, Hamby, Kelly, Russell, Maria, Strobert, Elizabeth, Blazar, Bruce R., Pearson, Thomas C., Larsen, Christian P., Kean, Leslie S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874242/
https://ncbi.nlm.nih.gov/pubmed/18801023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02376.x
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