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An MHC-defined primate model reveals significant rejection of bone marrow after mixed-chimerism induction despite full MHC matching
In murine models, mixed hematopoietic chimerism-induction leads to robust immune tolerance. However, translation to primates and to patients has been difficult. In this study, we used a novel MHC-defined rhesus macaque model to examine the impact of MHC matching on the stability of costimulation blo...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2980834/ https://ncbi.nlm.nih.gov/pubmed/20849552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2010.03272.x |
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