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Regulatory T cells Exhibit Decreased Proliferation but Enhanced Suppression After Pulsing with Sirolimus

Although regulatory T cells (Tregs) suppress allo-immunity, difficulties in their large-scale production and in maintaining their suppressive function after expansion have thus far limited their clinical applicability. Here we have used our non-human primate model to demonstrate that significant ex...

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Detalhes bibliográficos
Main Authors: Singh, K., Kozyr, N., Stempora, L., Kirk, A.D., Larsen, C.P., Blazar, B.R., Kean, L.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471086/
https://ncbi.nlm.nih.gov/pubmed/22300641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03963.x
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