CD4(+)FOXP3(+) Regulatory T Cells Exhibit Impaired Ability to Suppress Effector T Cell Proliferation in Patients with Turner Syndrome

OBJECTIVE: We investigated whether the frequency, phenotype, and suppressive function of CD4(+)FOXP3(+) regulatory T cells (Tregs) are altered in young TS patients with the 45,X karyotype compared to age-matched controls. DESIGN AND METHODS: Peripheral blood mononuclear cells from young TS patients...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Young Ah, Kim, Hang-Rae, Lee, Jeong Seon, Jung, Hae Woon, Kim, Hwa Young, Lee, Gyung Min, Lee, Jieun, Sim, Ji Hyun, Oh, Sae Jin, Chung, Doo Hyun, Shin, Choong Ho, Yang, Sei Won
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692523/
https://ncbi.nlm.nih.gov/pubmed/26709833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144549
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