Alloimmunization to transfused HOD RBCs is not increased in mice with sickle cell disease

BACKGROUND: Increased rates of RBC alloimmunization in patients with sickle cell disease may be due to transfusion frequency, genetic predisposition, or immune dysregulation. To test the hypothesis that sickle cell pathophysiology influences RBC alloimmunization, we utilized two transgenic mouse mod...

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Main Authors: Hendrickson, Jeanne E, Hod, Eldad A., Perry, Jennifer R., Chappa, Prasanthi, Adisa, Olufolake, Kean, Leslie S., Ofori-Acquah, Solomon F., Archer, David R., Spitalnik, Steven L., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218203/
https://ncbi.nlm.nih.gov/pubmed/21790627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1537-2995.2011.03255.x
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