Transfusion in the absence of inflammation induces antigen-specific tolerance to murine RBCs

Most human transfusion recipients fail to make detectable alloantibodies to foreign RBC antigens (“nonresponders”). Herein, we use a murine model to test the hypothesis that nonresponders may be immunologically tolerant. FVB mice transfused with RBCs expressing transgenic human glycophorin A (hGPA)...

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Bibliografiset tiedot
Päätekijät: Smith, Nicole H., Hod, Eldad A., Spitalnik, Steven L., Zimring, James C., Hendrickson, Jeanne E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2012
Aiheet:
Transfusion Medicine
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286217/
https://ncbi.nlm.nih.gov/pubmed/22077064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-382655
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