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Building a Safer and Faster CAR: Seatbelts, Airbags and CRISPR

Therapeutic T cell engineering has recently garnered widespread interest owing to the success of CD19 (Chimeric Antigen Receptor) CAR therapy. CARs are synthetic receptors for antigen that redirect the specificity and reprogram the function of the T cells in which they are genetically introduced. CA...

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Dettagli Bibliografici
Pubblicato in:Biol Blood Marrow Transplant
Autori principali: Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901894/
https://ncbi.nlm.nih.gov/pubmed/29032264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.10.017
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