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Building a Safer and Faster CAR: Seatbelts, Airbags and CRISPR

Therapeutic T cell engineering has recently garnered widespread interest owing to the success of CD19 (Chimeric Antigen Receptor) CAR therapy. CARs are synthetic receptors for antigen that redirect the specificity and reprogram the function of the T cells in which they are genetically introduced. CA...

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Detalles Bibliográficos
Publicado en:Biol Blood Marrow Transplant
Main Authors: Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901894/
https://ncbi.nlm.nih.gov/pubmed/29032264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.10.017
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