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Building a Safer and Faster CAR: Seatbelts, Airbags and CRISPR

Therapeutic T cell engineering has recently garnered widespread interest owing to the success of CD19 (Chimeric Antigen Receptor) CAR therapy. CARs are synthetic receptors for antigen that redirect the specificity and reprogram the function of the T cells in which they are genetically introduced. CA...

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Библиографические подробности
Опубликовано в: :Biol Blood Marrow Transplant
Главные авторы: Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901894/
https://ncbi.nlm.nih.gov/pubmed/29032264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.10.017
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