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Building a Safer and Faster CAR: Seatbelts, Airbags and CRISPR

Therapeutic T cell engineering has recently garnered widespread interest owing to the success of CD19 (Chimeric Antigen Receptor) CAR therapy. CARs are synthetic receptors for antigen that redirect the specificity and reprogram the function of the T cells in which they are genetically introduced. CA...

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Dades bibliogràfiques
Publicat a:Biol Blood Marrow Transplant
Autors principals: Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901894/
https://ncbi.nlm.nih.gov/pubmed/29032264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.10.017
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