Contribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment

द्वारा Kasembeli, Moses M., Bharadwaj, Uddalak, Robinson, Prema, Tweardy, David J.
में प्रकाशित Int J Mol Sci (2018)

Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

द्वारा Bharadwaj, Uddalak, Kasembeli, Moses M., Robinson, Prema, Tweardy, David J.
में प्रकाशित Pharmacol Rev (2020)

Contribution of chaperones to STAT pathway signaling

द्वारा Bocchini, Claire E, Kasembeli, Moses M, Roh, Soung-Hun, Tweardy, David J
में प्रकाशित JAKSTAT (2014)

Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation

द्वारा Xu, Xuejun, Kasembeli, Moses M., Jiang, Xueqing, Tweardy, Benjamin J., Tweardy, David J.
प्रकाशित 2009

Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions

द्वारा Roh, Soung-Hun, Kasembeli, Moses M., Galaz-Montoya, Jesús G., Chiu, Wah, Tweardy, David J.
में प्रकाशित Biophys J (2016)

Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer

द्वारा Bharadwaj, Uddalak, Kasembeli, Moses M., Eckols, T. Kris, Kolosov, Mikhail, Lang, Paul, Christensen, Kurt, Edwards, Dean P., Tweardy, David J.
में प्रकाशित Cancers (Basel) (2014)

SMALL-MOLECULE TARGETING OF SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION (STAT) 3 TO TREAT NON-SMALL CELL LUNG CANCER()

द्वारा Lewis, Katherine M., Bharadwaj, Uddalak, Eckols, T. Kris, Kolosov, Mikhail, Kasembeli, Moses M., Fridley, Colleen, Siller, Ricardo, Tweardy, David J.
में प्रकाशित Lung Cancer (2015)

Pharmacokinetics and pharmacodynamics of TTI-101, a STAT3 inhibitor that blocks muscle proteolysis in rats with chronic kidney disease

द्वारा Zhang, Liping, Wang, Ying, Dong, Yanlan, Chen, Zihong, Eckols, Thomas K., Kasembeli, Moses M., Tweardy, David J., Mitch, William E.
में प्रकाशित Am J Physiol Renal Physiol (2020)

Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome

द्वारा Bocchini, Claire E., Nahmod, Karen, Katsonis, Panagiotis, Kim, Sang, Kasembeli, Moses M., Freeman, Alexandra, Lichtarge, Olivier, Makedonas, George, Tweardy, David J.
में प्रकाशित Blood (2016)

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

द्वारा Bharadwaj, Uddalak, Eckols, T. Kris, Xu, Xuejun, Kasembeli, Moses M., Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y., Tweardy, David J.
में प्रकाशित Oncotarget (2016)

Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

द्वारा Bharadwaj, Uddalak, Eckols, T. Kris, Xu, Xuejun, Kasembeli, Moses M., Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y., Tweardy, David J.
में प्रकाशित Oncotarget (2019)

Rhodium(II) proximity-labeling identifies a novel target site on STAT3 for inhibitors with potent anti-leukemia activity

द्वारा Minus, Matthew B., Liu, Wei, Vohidov, Farrukh, Kasembeli, Moses M., Long, Xin, Krueger, Michael, Stevens, Alexandra, Kolosov, Mikhail I., Tweardy, David J., Sison, Edward Allen R., Redell, Michele S., Ball, Zachary T.
में प्रकाशित Angew Chem Int Ed Engl (2015)

Novel STAT3 Small-Molecule Inhibitors Identified by Structure-Based Virtual Ligand Screening Incorporating SH2 Domain Flexibility

द्वारा Kong, Ren, Bharadwaj, Uddalak, Eckols, T Kris, Kolosov, Mikhail, Wu, Haoyi, Cruz-Pavlovich, Francisco J. Santa, Shaw, Alison, Ifelayo, Oluwatomilona I., Zhao, Hong, Kasembeli, Moses M., Wong, Stephen T.C., Tweardy, David J
में प्रकाशित Pharmacol Res (2021)

Targeting STAT3 anti-apoptosis pathways with organic and hybrid organic–inorganic inhibitors

द्वारा Minus, Matthew B., Wang, Haopei, Munoz, Jaime O., Stevens, Alexandra M., Mangubat-Medina, Alicia E., Krueger, Michael J., Liu, Wei, Kasembeli, Moses M., Cooper, Julian C., Kolosov, Mikhail I., Tweardy, David J., Redell, Michele S., Ball, Zachary T.
में प्रकाशित Org Biomol Chem (2020)

DRUG-REPOSITIONING SCREENING IDENTIFIED PIPERLONGUMINE AS A DIRECT STAT3 INHIBITOR WITH POTENT ACTIVITY AGAINST BREAST CANCER

द्वारा Bharadwaj, Uddalak, Eckols, T. Kris, Kolosov, Mikhail, Kasembeli, Moses M., Adam, Abel, Torres, David, Zhang, Xiaomei, Dobrolecki, Lacey E., Wei, Wei, Lewis, Michael T., Dave, Bhuvanesh, Chang, Jenny C., Landis, Melissa D., Creighton, Chad J., Mancini, Michael A., Tweardy, David J.
प्रकाशित 2014