Clinical translation section: accelerating the pace from bench to bedside

Por Kandalaft, Lana E, Coukos, George
Publicado em 2011

A cancer vaccine with dendritic cells differentiated with GM-CSF and IFNα and pulsed with a squaric acid treated cell lysate improves T cell priming and tumor growth control in a m...

Por Mookerjee, Ananda, Graciotti, Michele, Kandalaft, Lana E.
Publicado no Bioimpacts (2018)

A phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous T cells for recurrent ovarian cancer

Por Kandalaft, Lana E, Powell, Daniel J, Coukos, George
Publicado em 2012

Whole Tumor Antigen Vaccines: Where Are We?

Por Chiang, Cheryl Lai-Lai, Coukos, George, Kandalaft, Lana E.
Publicado no Vaccines (Basel) (2015)

The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

Por Graciotti, Michele, Berti, Cristiana, Klok, Harm-Anton, Kandalaft, Lana
Publicado no J Transl Med (2017)

Endothelin B Receptor, a New Target in Cancer Immune Therapy

Por Kandalaft, Lana E., Facciabene, Andrea, Buckanovich, Ron J., Coukos, George
Publicado em 2009

Immunotherapy for Ovarian Cancer: What's Next?

Por Kandalaft, Lana E., Powell, Daniel J., Singh, Nathan, Coukos, George
Publicado em 2011

Cancer Vaccines in Ovarian Cancer: How Can We Improve?

Por Martin Lluesma, Silvia, Wolfer, Anita, Harari, Alexandre, Kandalaft, Lana E.
Publicado no Biomedicines (2016)

Ovarian cancer chemokines may not be a significant barrier during whole tumor antigen dendritic-cell vaccine and adoptive T-cell immunotherapy

Por Zsiros, Emese, Dangaj, Denarda, June, Carl H., Kandalaft, Lana E., Coukos, George
Publicado no Oncoimmunology (2015)

Differentially expressed nucleolar transforming growth factor-β1 target (DENTT) exhibits an inhibitory role on tumorigenesis

Por Kandalaft, Lana E., Zudaire, Enrique, Portal-Núñez, Sergio, Cuttitta, Frank, Jakowlew, Sonia B.
Publicado em 2008

Autologous whole-tumor antigen vaccination in combination with adoptive T cell therapy for patients with recurrent ovarian cancer

Por Kandalaft, Lana E, Chiang, Cheryl, Zsiros, Emese, Tanyi, Janos, Powell, Daniel, Mick, Rosemarie, Coukos, George
Publicado em 2013

A Phase I vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer

Por Kandalaft, Lana E, Chiang, Cheryl L, Tanyi, Janos, Motz, Greg, Balint, Klara, Mick, Rosemarie, Coukos, George
Publicado em 2013

The Emergence of Immunomodulation: Combinatorial Immuno-Chemotherapy Opportunities for the Next Decade

Por Kandalaft, Lana E., Singh, Nathan, Liao, John B., Facciabene, Andrea, Berek, Jonathan, Powell, Daniel J., Coukos, George
Publicado em 2009

Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity

Por Bassani-Sternberg, Michal, Chong, Chloé, Guillaume, Philippe, Solleder, Marthe, Pak, HuiSong, Gannon, Philippe O., Kandalaft, Lana E., Coukos, George, Gfeller, David
Publicado no PLoS Comput Biol (2017)

Day-4 Myeloid Dendritic Cells Pulsed with Whole Tumor Lysate Are Highly Immunogenic and Elicit Potent Anti-Tumor Responses

Por Chiang, Cheryl Lai-Lai, Hagemann, Andrea R., Leskowitz, Rachel, Mick, Rosemarie, Garrabrant, Thomas, Czerniecki, Brian J., Kandalaft, Lana E., Powell, Daniel J., Coukos, George
Publicado em 2011

Optimizing parameters for clinical-scale production of high IL-12 secreting dendritic cells pulsed with oxidized whole tumor cell lysate

Por Chiang, Cheryl L-L, Maier, Dawn A, Kandalaft, Lana E, Brennan, Andrea L, Lanitis, Evripidis, Ye, Qunrui, Levine, Bruce L, Czerniecki, Brian J, Powell Jr, Daniel J, Coukos, George
Publicado em 2011

Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer

Por Kandalaft, Lana E., Powell, Daniel J., Chiang, Cheryl L., Tanyi, Janos, Kim, Sarah, Bosch, Marnix, Montone, Kathy, Mick, Rosemarie, Levine, Bruce L., Torigian, Drew A., June, Carl H., Coukos, George
Publicado em 2013

The Ovarian Cancer Chemokine Landscape is Conducive to Homing of Vaccine-primed and CD3/CD28 Costimulated T cells Prepared for Adoptive Therapy

Por Zsiros, Emese, Duttagupta, Priyanka, Dangaj, Denarda, Li, Hongzhe, Frank, Renee, Garrabrant, Thomas, Hagemann, Ian S., Levine, Bruce L., June, Carl H., Zhang, Lin, Wang, Ena, Marincola, Francesco M., Bedognetti, Davide, Powell, Daniel J., Tanyi, Janos, Feldman, Michael D., Kandalaft, Lana E., Coukos, George
Publicado no Clin Cancer Res (2015)

A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside

Por Chiang, Cheryl Lai-Lai, Kandalaft, Lana E., Tanyi, Janos, Hagemann, Andrea R., Motz, Gregory T., Svoronos, Nikolaos, Montone, Kathleen, Mantia-Smaldone, Gina M., Nisenbaum, Harvey L., Levine, Bruce L., Kalos, Michael, Czerniecki, Brian J., Torigian, Drew A., Powell, Daniel J., Mick, Rosemarie, Smith, Lori, Coukos, George
Publicado em 2013

T cell–induced CSF1 promotes melanoma resistance to PD1 blockade

Por Neubert, Natalie J., Schmittnaegel, Martina, Bordry, Natacha, Nassiri, Sina, Wald, Noémie, Martignier, Christophe, Tillé, Laure, Homicsko, Krisztian, Damsky, William, Maby-El Hajjami, Hélène, Klaman, Irina, Danenberg, Esther, Ioannidou, Kalliopi, Kandalaft, Lana, Coukos, George, Hoves, Sabine, Ries, Carola H., Fuertes Marraco, Silvia A., Foukas, Periklis G., De Palma, Michele, Speiser, Daniel E.
Publicado no Sci Transl Med (2018)