The Ovarian Cancer Chemokine Landscape is Conducive to Homing of Vaccine-primed and CD3/CD28 Costimulated T cells Prepared for Adoptive Therapy

PURPOSE: Chemokines are implicated in T cell trafficking. We mapped the chemokine landscape in advanced stage ovarian cancer and characterized the expression of cognate receptors in autologous DC-vaccine primed T cells in the context of cell-based immunotherapy. EXPERIMENTAL DESIGN: The expression o...

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Udgivet i:Clin Cancer Res
Main Authors: Zsiros, Emese, Duttagupta, Priyanka, Dangaj, Denarda, Li, Hongzhe, Frank, Renee, Garrabrant, Thomas, Hagemann, Ian S., Levine, Bruce L., June, Carl H., Zhang, Lin, Wang, Ena, Marincola, Francesco M., Bedognetti, Davide, Powell, Daniel J., Tanyi, Janos, Feldman, Michael D., Kandalaft, Lana E., Coukos, George
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987088/
https://ncbi.nlm.nih.gov/pubmed/25712684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2777
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