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Autologous lysate-pulsed dendritic cell vaccination followed by adoptive transfer of vaccine-primed ex vivo co-stimulated T cells in recurrent ovarian cancer

Novel strategies for the therapy of recurrent ovarian cancer are warranted. We report a study of a combinatorial approach encompassing dendritic cell (DC)-based autologous whole tumor vaccination and anti-angiogenesis therapy, followed by the adoptive transfer of autologous vaccine-primed CD3/CD28-c...

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Detalhes bibliográficos
Main Authors: Kandalaft, Lana E., Powell, Daniel J., Chiang, Cheryl L., Tanyi, Janos, Kim, Sarah, Bosch, Marnix, Montone, Kathy, Mick, Rosemarie, Levine, Bruce L., Torigian, Drew A., June, Carl H., Coukos, George
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583933/
https://ncbi.nlm.nih.gov/pubmed/23482679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22664
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