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Endothelin B Receptor, a New Target in Cancer Immune Therapy

The endothelins and their G protein-coupled receptors A and B have been implicated innumerous diseases and have recently emerged as pivotal players in a variety of malignancies. Tumors over-express the endothelin 1 (ET-1) ligand and the endothelin-A-receptor (ET(A)R). Their interaction induces tumor...

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Main Authors: Kandalaft, Lana E., Facciabene, Andrea, Buckanovich, Ron J., Coukos, George
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896814/
https://ncbi.nlm.nih.gov/pubmed/19567593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0543
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