Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity

The precise identification of Human Leukocyte Antigen class I (HLA-I) binding motifs plays a central role in our ability to understand and predict (neo-)antigen presentation in infectious diseases and cancer. Here, by exploiting co-occurrence of HLA-I alleles across ten newly generated as well as fo...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Bassani-Sternberg, Michal, Chong, Chloé, Guillaume, Philippe, Solleder, Marthe, Pak, HuiSong, Gannon, Philippe O., Kandalaft, Lana E., Coukos, George, Gfeller, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584980/
https://ncbi.nlm.nih.gov/pubmed/28832583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005725
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi