Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity

The precise identification of Human Leukocyte Antigen class I (HLA-I) binding motifs plays a central role in our ability to understand and predict (neo-)antigen presentation in infectious diseases and cancer. Here, by exploiting co-occurrence of HLA-I alleles across ten newly generated as well as fo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Bassani-Sternberg, Michal, Chong, Chloé, Guillaume, Philippe, Solleder, Marthe, Pak, HuiSong, Gannon, Philippe O., Kandalaft, Lana E., Coukos, George, Gfeller, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584980/
https://ncbi.nlm.nih.gov/pubmed/28832583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005725
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