Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis

by Rabe, Patrick, Kamps, Jos J. A. G., Schofield, Christopher J., Lohans, Christopher T.
Published in Nat Prod Rep (2018)

The plant cysteine oxidases from Arabidopsis thaliana are kinetically tailored to act as oxygen sensors

by White, Mark D., Kamps, Jos J. A. G., East, Samuel, Taylor Kearney, Leah J., Flashman, Emily
Published in J Biol Chem (2018)

(19)F NMR studies on γ-butyrobetaine hydroxylase provide mechanistic insights and suggest a dual inhibition mode

by Leśniak, Robert K., Rydzik, Anna M., Kamps, Jos J. A. G., Kahn, Amjad, Claridge, Timothy D. W., Schofield, Christopher J.
Published in Chem Commun (Camb) (2019)

Cation–π Interactions Contribute to Substrate Recognition in γ‐Butyrobetaine Hydroxylase Catalysis

by Kamps, Jos J. A. G., Khan, Amjad, Choi, Hwanho, Lesniak, Robert K., Brem, Jürgen, Rydzik, Anna M., McDonough, Michael A., Schofield, Christopher J., Claridge, Timothy D. W., Mecinović, Jasmin
Published in Chemistry (2015)

Chemical basis for the recognition of trimethyllysine by epigenetic reader proteins

by Kamps, Jos J.A.G., Huang, Jiaxin, Poater, Jordi, Xu, Chao, Pieters, Bas J.G.E., Dong, Aiping, Min, Jinrong, Sherman, Woody, Beuming, Thijs, Matthias Bickelhaupt, F., Li, Haitao, Mecinović, Jasmin
Published in Nat Commun (2015)

Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins

by Belle, Roman, Kamps, Jos J. A. G., Poater, Jordi, Kumar, Kiran, Pieters, Bas J. G. E., Salah, Eidarus, Claridge, Timothy D. W., Paton, Robert S., Bickelhaupt, F. Matthias, Kawamura, Akane, Schofield, Christopher J., Mecinović, Jasmin
Published in Commun Chem (2022)

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

by Krajnc, Alen, Brem, Jürgen, Hinchliffe, Philip, Calvopiña, Karina, Panduwawala, Tharindi D., Lang, Pauline A., Kamps, Jos J. A. G., Tyrrell, Jonathan M., Widlake, Emma, Saward, Benjamin G., Walsh, Timothy R., Spencer, James, Schofield, Christopher J.
Published in J Med Chem (2019)

Non‐Hydrolytic β‐Lactam Antibiotic Fragmentation by l,d‐Transpeptidases and Serine β‐Lactamase Cysteine Variants

by Lohans, Christopher T., Chan, H. T. Henry, Malla, Tika R., Kumar, Kiran, Kamps, Jos J. A. G., McArdle, Darius J. B., van Groesen, Emma, de Munnik, Mariska, Tooke, Catherine L., Spencer, James, Paton, Robert S., Brem, Jürgen, Schofield, Christopher J.
Published in Angew Chem Int Ed Engl (2019)

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

by Zhang, Dong, Markoulides, Marios S., Stepanovs, Dmitrijs, Rydzik, Anna M., El-Hussein, Ahmed, Bon, Corentin, Kamps, Jos J.A.G., Umland, Klaus-Daniel, Collins, Patrick M., Cahill, Samuel T., Wang, David Y., von Delft, Frank, Brem, Jürgen, McDonough, Michael A., Schofield, Christopher J.
Published in Bioorg Med Chem (2018)

An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography

by Butryn, Agata, Simon, Philipp S., Aller, Pierre, Hinchliffe, Philip, Massad, Ramzi N., Leen, Gabriel, Tooke, Catherine L., Bogacz, Isabel, Kim, In-Sik, Bhowmick, Asmit, Brewster, Aaron S., Devenish, Nicholas E., Brem, Jürgen, Kamps, Jos J. A. G., Lang, Pauline A., Rabe, Patrick, Axford, Danny, Beale, John H., Davy, Bradley, Ebrahim, Ali, Orlans, Julien, Storm, Selina L. S., Zhou, Tiankun, Owada, Shigeki, Tanaka, Rie, Tono, Kensuke, Evans, Gwyndaf, Owen, Robin L., Houle, Frances A., Sauter, Nicholas K., Schofield, Christopher J., Spencer, James, Yachandra, Vittal K., Yano, Junko, Kern, Jan F., Orville, Allen M.
Published in Nat Commun (2021)