The acidic pathway of bile acid synthesis: Not just an alternative pathway(☆)

ανά Pandak, William M., Kakiyama, Genta
Τόπος έκδοσης Liver Res (2019)

Liver-specific transgenic expression of cholesteryl ester hydrolase reduces atherosclerosis in Ldlr(−/−) mice

ανά Bie, Jinghua, Wang, Jing, Yuan, Quan, Kakiyama, Genta, Ghosh, Siddhartha S., Ghosh, Shobha
Έκδοση 2014

Sterol carrier protein-2 deficiency attenuates diet-induced dyslipidemia and atherosclerosis in mice

ανά He, Hongliang, Wang, Jing, Yannie, Paul J., Kakiyama, Genta, Korzun, William J., Ghosh, Shobha
Τόπος έκδοσης J Biol Chem (2018)

Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro

ανά Zhang, Xin, Bai, Qianming, Xu, Leyuan, Kakiyama, Genta, Pandak, William M., Zhang, Zhigang, Ren, Shunlin
Έκδοση 2012

Cholesterol metabolite, 5-cholesten-3beta, 25-diol 3-sulfate, promotes hepatic proliferation in mice

ανά Zhang, Xin, Bai, Qianming, Kakiyama, Genta, Xu, Leyuan, Kim, Jin Kyung, Pandak, William M., Ren, Shunlin
Έκδοση 2012

Liver-specific Cholesteryl Ester Hydrolase deficiency attenuates sterol elimination in the feces and increases Atherosclerosis in Ldlr-/- Mice

ανά Bie, Jinghua, Wang, Jing, Marqueen, Kathryn E, Osborne, Rachel, Kakiyama, Genta, Korzun, William, Ghosh, Siddhartha S, Ghosh, Shobha
Έκδοση 2013

Identification of Novel Regulatory Cholesterol Metabolite, 5-Cholesten, 3β,25-Diol, Disulfate

ανά Ren, Shunlin, Kim, Jin Koung, Kakiyama, Genta, Rodriguez-Agudo, Daniel, Pandak, William M., Min, Hae-Ki, Ning, Yanxia
Έκδοση 2014

Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells

ανά Bai, Qianming, Xu, Leyuan, Kakiyama, Genta, Runge-Morris, Melissa Ann, Hylemon, Phillip B., Yin, Lianhua, Pandak, William M., Ren, Shunlin
Έκδοση 2010

A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS

ανά Kakiyama, Genta, Muto, Akina, Takei, Hajime, Nittono, Hiroshi, Murai, Tsuyoshi, Kurosawa, Takao, Hofmann, Alan F., Pandak, William M., Bajaj, Jasmohan S.
Έκδοση 2014

Oxysterol Sulfation by SULT2B1b Suppresses LXR/SREBP-1c Signaling Pathway and Reduces Serum and Hepatic Lipids in Mouse Models of NAFLD

ανά Bai, Qianming, Zhang, Xin, Xu, Leyuan, Kakiyama, Genta, Heuman, Douglas, Sanyal, Arun, Pandak, William M., Yin, Lianhua, Xie, Wen, Ren, Shunlin
Έκδοση 2012

5-Cholesten-3β,25-Diol 3-Sulfate Decreases Lipid Accumulation in Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model

ανά Xu, Leyuan, Kim, Jin Koung, Bai, Qianming, Zhang, Xin, Kakiyama, Genta, Min, Hae-ki, Sanyal, Arun J., Pandak, William M., Ren, Shunlin
Έκδοση 2013

A new, major C(27) biliary bile acid in the Red-winged tinamou (Rhynchotus rufescens):(25R)-1β,3α,7α-trihydroxy-5β-cholestan-27-oic acid

ανά Hagey, Lee R., Kakiyama, Genta, Muto, Akina, Iida, Takashi, Mushiake, Kumiko, Goto, Takaaki, Mano, Nariyasu, Goto, Junichi, Oliveira, Cleida A., Hofmann, Alan F.
Έκδοση 2009

StarD5: an ER stress protein regulates plasma membrane and intracellular cholesterol homeostasis

ανά Rodriguez-Agudo, Daniel, Malacrida, Leonel, Kakiyama, Genta, Sparrer, Tavis, Fortes, Carolina, Maceyka, Michael, Subler, Mark A., Windle, Jolene J., Gratton, Enrico, Pandak, William M., Gil, Gregorio
Τόπος έκδοσης J Lipid Res (2019)

Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine

ανά Wen, Jia, Mercado, Gilberto Padilla, Volland, Alyssa, Doden, Heidi L., Lickwar, Colin R., Crooks, Taylor, Kakiyama, Genta, Kelly, Cecelia, Cocchiaro, Jordan L., Ridlon, Jason M., Rawls, John F.
Τόπος έκδοσης Sci Adv (2021)

Bile Acid 7α-Dehydroxylating Gut Bacteria Secrete Antibiotics that Inhibit Clostridium difficile: Role of Secondary Bile Acids

ανά Kang, Jason D., Myers, Christopher J., Harris, Spencer C., Kakiyama, Genta, Lee, In-Kyoung, Yun, Bong-Sik, Matsuzaki, Keiichi, Furukawa, Megumi, Min, Hae-Ki, Bajaj, Jasmohan S., Zhou, Huiping, Hylemon, Phillip B.
Τόπος έκδοσης Cell Chem Biol (2018)

Alterations in Skin Microbiomes of Patients With Cirrhosis

ανά Bajaj, Jasmohan S, Fagan, Andrew, Sikaroodi, Masoumeh, Kakiyama, Genta, Takei, Hajme, Degefu, Yordanos, Pandak, William M, Hylemon, Phillip B, Fuchs, Michael, John, Binu, Heuman, Douglas M, Gavis, Edith, Nittono, Hiroshi, Patil, Rohan, Gillevet, Patrick M
Τόπος έκδοσης Clin Gastroenterol Hepatol (2019)

Berberine Prevents Disease Progression of Nonalcoholic Steatohepatitis through Modulating Multiple Pathways

ανά Wang, Yanyan, Tai, Yun-Ling, Zhao, Derrick, Zhang, Yuan, Yan, Junkai, Kakiyama, Genta, Wang, Xuan, Gurley, Emily C., Liu, Jinze, Liu, Jinpeng, Liu, Jimin, Lai, Guanhua, Hylemon, Phillip B., Pandak, William M., Chen, Weidong, Zhou, Huiping
Τόπος έκδοσης Cells (2021)

Colonic inflammation and secondary bile acids in alcoholic cirrhosis

ανά Kakiyama, Genta, Hylemon, Phillip B., Zhou, Huiping, Pandak, William M., Heuman, Douglas M., Kang, Dae Joong, Takei, Hajime, Nittono, Hiroshi, Ridlon, Jason M., Fuchs, Michael, Gurley, Emily C., Wang, Yun, Liu, Runping, Sanyal, Arun J., Gillevet, Patrick M., Bajaj, Jasmohan S.
Έκδοση 2014

Gut microbial composition can differentially regulate bile acid synthesis in humanized mice

ανά Kang, Dae Joong, Hylemon, Phillip B, Gillevet, Patrick M, Sartor, R. Balfour, Betrapally, Naga S., Kakiyama, Genta, Sikaroodi, Masoumeh, Takei, Hajime, Nittono, Hiroshi, Zhou, Huiping, Pandak, William M., Yang, Jing, Jiao, Chunhua, Li, Xiaojiaoyang, Lippman, H. Robert, Heuman, Douglas M., Bajaj, Jasmohan S.
Τόπος έκδοσης Hepatol Commun (2017)

Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition

ανά Kakiyama, Genta, Marques, Dalila, Martin, Rebecca, Takei, Hajime, Rodriguez-Agudo, Daniel, LaSalle, Sandra A., Hashiguchi, Taishi, Liu, Xiaoying, Green, Richard, Erickson, Sandra, Gil, Gregorio, Fuchs, Michael, Suzuki, Mitsuyoshi, Murai, Tsuyoshi, Nittono, Hiroshi, Hylemon, Phillip B., Zhou, Huiping, Pandak, William M.
Τόπος έκδοσης J Lipid Res (2020)